What Is a Polynucleotide Facial?
In aesthetics, one ingredient is creating serious buzz: polynucleotides, also known as salmon sperm DNA. Celebrities, beauty editors, and dermatologists are all talking about this new category of biostimulators – powerful ingredients that trigger the skin to regenerate from within.
A polynucleotide facial uses highly purified salmon DNA to repair cellular damage, boost collagen and elastin production, and improve hydration. Unlike traditional skincare that sits on the surface, polynucleotides actually reprogram skin cells to behave like younger, healthier versions of themselves.
At KICHI, we’ve gone a step further. We’ve developed a needle-free delivery method that allows clients to experience the benefits of polynucleotides without injectables.
The Science Behind Salmon DNA Skincare
What Are Polynucleotides?
Polynucleotides (PNs) are long chains of DNA fragments. In skin treatments, they are typically extracted from purified salmon sperm DNA, chosen because of its close structural similarity to human DNA. This similarity means the body recognises and utilises it efficiently, making it both safe and highly effective.
How Do Polynucleotides Work?
Polynucleotides are classed as biostimulators. Unlike fillers (which add volume) or hyaluronic acid (which hydrates), polynucleotides work by:
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Activating fibroblasts – the cells that produce collagen and elastin
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Repairing DNA damage caused by oxidative stress, UV exposure, and ageing
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Binding water molecules for deep hydration and tissue support
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Improving microcirculation and oxygen supply to skin cells
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Restoring elasticity and thickness by regenerating the extracellular matrix
In clinical studies, polynucleotides have been shown to accelerate wound healing, reduce inflammation, and improve overall skin quality. The results are not temporary – they rebuild the skin’s architecture, creating lasting improvement.
Why Salmon DNA?
Salmon sperm DNA is one of the most widely used sources of polynucleotides because:
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It is biocompatible with human skin
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It has a high safety profile and low risk of rejection
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It can be purified to pharmaceutical-grade standards
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It has been studied in regenerative medicine for decades
This is why salmon DNA has become the gold standard in polynucleotide skincare and facial treatments.
Why Choose a No-Needle Polynucleotide Treatment?
Traditionally, polynucleotides are delivered through injections, similar to dermal fillers. While effective, injectables aren’t for everyone – some clients dislike needles, while others want a less invasive option.
At KICHI, we’ve pioneered a no-needle polynucleotide facial that delivers up to 90% absorption into the skin – compared to just 2–5% from topical serums.
We achieve this with two advanced delivery systems:
1. Thulium Laser (Level 1)
A gentle, non-ablative laser that creates micro-channels in the skin. These channels allow polynucleotides to penetrate deeply without damage. The laser has zero downtime, meaning you can leave the studio glowing, not peeling.
2. Microneedling
A proven method for enhancing absorption, microneedling also stimulates collagen on its own. When combined with polynucleotides, it supercharges regeneration.
Together, these methods make our no-needle polynucleotide facial unique in the UK – offering injectable-level benefits without injections.
Benefits of a Polynucleotide Facial at KICHI
Clients who experience our salmon DNA facial typically report:
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Tighter, firmer skin with improved elasticity
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Reduction in fine lines and wrinkles
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Improved hydration and luminosity
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Repair of sun damage and inflammation
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A smoother, plumper complexion
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Faster healing and resilience after skin stress
Because polynucleotides are regenerative rather than temporary, the results build over time – making this an excellent treatment for collagen banking and long-term skin health.
Polynucleotides vs. Other Skin Treatments
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Topical skincare: Only penetrates the outer layers (2–5% absorption)
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Injectables: Highly effective but invasive and needle-based
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KICHI no-needle method: Combines laser and microneedling for 90% absorption, zero downtime, and a comfortable, non-invasive experience
Who Is It For?
A polynucleotide facial is ideal for:
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Clients curious about polynucleotides but not ready for injectables
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Men and women wanting skin regeneration without downtime
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Anyone seeking a future-focused, biotech skincare solution
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People with early signs of ageing, dehydration, or environmental damage
The Future of Biostimulation in Skincare
Biostimulators like polynucleotides represent the future of aesthetics. Rather than filling, freezing, or resurfacing, they teach the skin to regenerate itself.
At KICHI, our ethos has always been to future-proof your skin by using the most advanced, scientifically backed solutions. By offering salmon DNA facials without needles, we’re making one of the most powerful skin technologies accessible in a way that’s elegant, comfortable, and effective.
FAQs About Polynucleotide Facials
Is salmon sperm DNA safe for skin?
Yes. Salmon DNA is highly purified and biocompatible with human skin. Clinical studies have shown it to be safe, with minimal risk of reaction.
Do polynucleotide facials really work without injections?
Yes. Our no-needle method uses laser and microneedling to achieve up to 90% absorption – comparable to injectables.
How many treatments will I need?
For best results, we recommend a course of 3–6 treatments, spaced 3–4 weeks apart, followed by maintenance every few months.
What’s the downtime?
Zero. You can return to work or social plans immediately after your facial.
What results can I expect?
Hydrated, plumper, smoother skin with improved tone and elasticity. Results are cumulative and build with each treatment.
